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primerarray jak stat signaling pathway human qpcr array  (TaKaRa)


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    TaKaRa primerarray jak stat signaling pathway human qpcr array
    Figure 2. TYK2 inhibition leads to compensatory stimulation of the MAPK pathway in MPNST cells. A, JH-2–002 cells were treated with 40 mmol/L WU-12 or control for 48 hours, and gene expression was analyzed by <t>qPCR</t> array for JAK/STAT pathway–related genes. Log2 fold changes of significantly changed genes are graphed. B, JW23.3 cellswere treated with control or 40 mmol/LWU-12 or WU-76 for 48 hours. Global gene expressionwas determined byRNA-seq pathway analysis. Changes in gene expression for WU-12 versus control were examined by RNA-seq for genes downstream of STAT3 in a heatmap (C) and boxplot (D), as well as MEK/MAPK pathway genes in a volcano plot (E), enrichment plot (F), and boxplot (G). P < 0.05 vs. vehicle control.
    Primerarray Jak Stat Signaling Pathway Human Qpcr Array, supplied by TaKaRa, used in various techniques. Bioz Stars score: 93/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/primerarray jak stat signaling pathway human qpcr array/product/TaKaRa
    Average 93 stars, based on 3 article reviews
    primerarray jak stat signaling pathway human qpcr array - by Bioz Stars, 2026-06
    93/100 stars

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    1) Product Images from "MEK Inhibition Synergizes with TYK2 Inhibitors in NF1-Associated Malignant Peripheral Nerve Sheath Tumors"

    Article Title: MEK Inhibition Synergizes with TYK2 Inhibitors in NF1-Associated Malignant Peripheral Nerve Sheath Tumors

    Journal: Clinical Cancer Research

    doi: 10.1158/1078-0432.ccr-22-3722

    Figure 2. TYK2 inhibition leads to compensatory stimulation of the MAPK pathway in MPNST cells. A, JH-2–002 cells were treated with 40 mmol/L WU-12 or control for 48 hours, and gene expression was analyzed by qPCR array for JAK/STAT pathway–related genes. Log2 fold changes of significantly changed genes are graphed. B, JW23.3 cellswere treated with control or 40 mmol/LWU-12 or WU-76 for 48 hours. Global gene expressionwas determined byRNA-seq pathway analysis. Changes in gene expression for WU-12 versus control were examined by RNA-seq for genes downstream of STAT3 in a heatmap (C) and boxplot (D), as well as MEK/MAPK pathway genes in a volcano plot (E), enrichment plot (F), and boxplot (G). P < 0.05 vs. vehicle control.
    Figure Legend Snippet: Figure 2. TYK2 inhibition leads to compensatory stimulation of the MAPK pathway in MPNST cells. A, JH-2–002 cells were treated with 40 mmol/L WU-12 or control for 48 hours, and gene expression was analyzed by qPCR array for JAK/STAT pathway–related genes. Log2 fold changes of significantly changed genes are graphed. B, JW23.3 cellswere treated with control or 40 mmol/LWU-12 or WU-76 for 48 hours. Global gene expressionwas determined byRNA-seq pathway analysis. Changes in gene expression for WU-12 versus control were examined by RNA-seq for genes downstream of STAT3 in a heatmap (C) and boxplot (D), as well as MEK/MAPK pathway genes in a volcano plot (E), enrichment plot (F), and boxplot (G). P < 0.05 vs. vehicle control.

    Techniques Used: Inhibition, Control, Gene Expression, RNA Sequencing



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    primerarray jak stat signaling pathway human qpcr array  (TaKaRa)
    93
    TaKaRa primerarray jak stat signaling pathway human qpcr array
    Figure 2. TYK2 inhibition leads to compensatory stimulation of the MAPK pathway in MPNST cells. A, JH-2–002 cells were treated with 40 mmol/L WU-12 or control for 48 hours, and gene expression was analyzed by <t>qPCR</t> array for JAK/STAT pathway–related genes. Log2 fold changes of significantly changed genes are graphed. B, JW23.3 cellswere treated with control or 40 mmol/LWU-12 or WU-76 for 48 hours. Global gene expressionwas determined byRNA-seq pathway analysis. Changes in gene expression for WU-12 versus control were examined by RNA-seq for genes downstream of STAT3 in a heatmap (C) and boxplot (D), as well as MEK/MAPK pathway genes in a volcano plot (E), enrichment plot (F), and boxplot (G). P < 0.05 vs. vehicle control.
    Primerarray Jak Stat Signaling Pathway Human Qpcr Array, supplied by TaKaRa, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/primerarray jak stat signaling pathway human qpcr array/product/TaKaRa
    Average 93 stars, based on 1 article reviews
    primerarray jak stat signaling pathway human qpcr array - by Bioz Stars, 2026-06
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    Figure 2. TYK2 inhibition leads to compensatory stimulation of the MAPK pathway in MPNST cells. A, JH-2–002 cells were treated with 40 mmol/L WU-12 or control for 48 hours, and gene expression was analyzed by qPCR array for JAK/STAT pathway–related genes. Log2 fold changes of significantly changed genes are graphed. B, JW23.3 cellswere treated with control or 40 mmol/LWU-12 or WU-76 for 48 hours. Global gene expressionwas determined byRNA-seq pathway analysis. Changes in gene expression for WU-12 versus control were examined by RNA-seq for genes downstream of STAT3 in a heatmap (C) and boxplot (D), as well as MEK/MAPK pathway genes in a volcano plot (E), enrichment plot (F), and boxplot (G). P < 0.05 vs. vehicle control.

    Journal: Clinical Cancer Research

    Article Title: MEK Inhibition Synergizes with TYK2 Inhibitors in NF1-Associated Malignant Peripheral Nerve Sheath Tumors

    doi: 10.1158/1078-0432.ccr-22-3722

    Figure Lengend Snippet: Figure 2. TYK2 inhibition leads to compensatory stimulation of the MAPK pathway in MPNST cells. A, JH-2–002 cells were treated with 40 mmol/L WU-12 or control for 48 hours, and gene expression was analyzed by qPCR array for JAK/STAT pathway–related genes. Log2 fold changes of significantly changed genes are graphed. B, JW23.3 cellswere treated with control or 40 mmol/LWU-12 or WU-76 for 48 hours. Global gene expressionwas determined byRNA-seq pathway analysis. Changes in gene expression for WU-12 versus control were examined by RNA-seq for genes downstream of STAT3 in a heatmap (C) and boxplot (D), as well as MEK/MAPK pathway genes in a volcano plot (E), enrichment plot (F), and boxplot (G). P < 0.05 vs. vehicle control.

    Article Snippet: Phosphorylated protein levels were normalized to the respective total protein levels and expressed as a percent of control for each time point. qPCR pathway array The effect of WU-12 on gene expression of potential downstream targets known to be in the JAK–STAT pathway was assessed by a PrimerArray JAK–STAT Signaling Pathway (Human) qPCR array in 96-well plate format (Takara Bio).

    Techniques: Inhibition, Control, Gene Expression, RNA Sequencing